On the other hand , a positive inotropic response was induced by il - 2 in isolated rat atria , indirectly by activating myocardial 3 - adrenoceptors by release of catecholamines , and directly by increasing the production of second messenger camp . in the isolated rat heart , stimulation of cardiac k opioid receptors has been shown to induce ventricular ectopic beats and to reduce the force of ventricular contraction 通過(guò)文獻(xiàn)調(diào)研和我們的預(yù)實(shí)驗(yàn),我們假設(shè), il - 2的心臟作用涉及心肌細(xì)胞收縮力和細(xì)胞內(nèi)鈣的變化,其信號(hào)轉(zhuǎn)導(dǎo)途徑可能并非通過(guò)自身受體,而是通過(guò)存在于心肌細(xì)胞膜上的阿片受體發(fā)揮作用的;其對(duì)血管的作用可能循相關(guān)途徑。
百科解釋
Ectopic beat (or cardiac ectopy) is a disturbance of the cardiac rhythm frequently related to the electrical conduction system of the heart, in which beats arise from fiber or group of fibers outside the region in the heart muscle ordinarily responsible for impulse formation, i.e.